Abstract

Conclusions: Acute GI toxicity during definitive RT for anal cancer was most significant during weeks 4-5, while rectal bleeding improved during treatment. The discrepancies in patient and clinician reported symptoms of proctitis are consistent with studies in rectal cancer, and demonstrate the potential for patient-reported outcomes to be useful tools for anal cancer clinical assessments. Additional research is needed to explore ways these assessments can improve management of treatment-related toxicity. Author Disclosure: A. Tom: None. A. Bennett: None. D. Rothenstein: None. S. Milgrom: None. E. Law: None. E. Mangarin: None. A. Wu: None. K.A. Goodman: None.

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