Abstract
Introduction: Intersphinteric resection (ISR) allows preserve sphincter function in selected patients with rectal cancer (RC). Notwithstanding, it can produce alterations in defecation. Aim: To analyze the oncological and functional results after an ISR. Materials and Method: Observational, analytical, cross-sectional study, in the period 2007-2016. Inclusion criteria: Patients submitted to ISR by RC with curative intention. All the patients had a follow-up in 2017. Analysis of functional evaluation were performed by Jorge- Wexner, LARS and Kirwan scale. Statistical analysis: Descriptive statistics and Kaplan-Meier method. Results: Of 21 patients; Fourteen (67%) were male, average age: 59 years. Tumor location: 4 cm (2-6 cm) from anal verge. Eighteen (85.7%) patients received neoadjuvant therapy. All distal and radial margins were negative. One patient (4.8%) had distant metastases and there was no locoregional recurrence. With a median follow-up of 76.3 (9.8-126.8) months, the 5-year global and disease-free survival was: 100% and 95% (CI: 90.1-99.9%), respectively. With a median follow-up of 90 months (21.7-124.2); Functional evaluation was performed on 15/21 patients. The Jorge-Wexner score had a median of 13 (4-17) points, the LARS scale of 34 points and in Kirwan scale, four patients (26.7%) showed good function (Kirwan I-II). Conclusion: The oncological results of patients undergoing ISR are satisfactory, however, functional results should be taken into account when proposing this surgical procedure.
Highlights
Intersphinteric resection (ISR) allows preserve sphincter function in selected patients with rectal cancer (RC)
Inclusion criteria: Patients submitted to ISR by RC with curative intention
Analysis of functional evaluation were performed by JorgeWexner, LARS and Kirwan scale
Summary
Intersphinteric resection (ISR) allows preserve sphincter function in selected patients with rectal cancer (RC). A mediados de los 90 Schiessel et al, proponen la resección anterior ultrabaja interesfintérica (RAUBIE); que además de obtener resultados oncológicos aceptables, permite preservar la mayor parte del complejo esfinteriano en pacientes seleccionados con un cáncer en los últimos 5 cm del recto siendo una alternativa a la RAP5,6. Si bien es cierto la RAUBIE permite preservar la mayor parte del complejo esfinteriano, puede producir alteraciones en la función evacuatoria que va a depender del nivel de la sección distal del esfínter anal interno (parcial, subtotal, extendida o total); lo que se acompañará de un grado variable de incontinencia fecal sumado al síndrome de resección anterior baja (síndrome LARS). El objetivo del presente estudio es analizar los resultados oncológicos y funcionales a largo plazo luego de una RAUBIE en pacientes con adenocarcinoma del recto inferior
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