Abstract

Introduction: Intersphinteric resection (ISR) allows preserve sphincter function in selected patients with rectal cancer (RC). Notwithstanding, it can produce alterations in defecation. Aim: To analyze the oncological and functional results after an ISR. Materials and Method: Observational, analytical, cross-sectional study, in the period 2007-2016. Inclusion criteria: Patients submitted to ISR by RC with curative intention. All the patients had a follow-up in 2017. Analysis of functional evaluation were performed by Jorge- Wexner, LARS and Kirwan scale. Statistical analysis: Descriptive statistics and Kaplan-Meier method. Results: Of 21 patients; Fourteen (67%) were male, average age: 59 years. Tumor location: 4 cm (2-6 cm) from anal verge. Eighteen (85.7%) patients received neoadjuvant therapy. All distal and radial margins were negative. One patient (4.8%) had distant metastases and there was no locoregional recurrence. With a median follow-up of 76.3 (9.8-126.8) months, the 5-year global and disease-free survival was: 100% and 95% (CI: 90.1-99.9%), respectively. With a median follow-up of 90 months (21.7-124.2); Functional evaluation was performed on 15/21 patients. The Jorge-Wexner score had a median of 13 (4-17) points, the LARS scale of 34 points and in Kirwan scale, four patients (26.7%) showed good function (Kirwan I-II). Conclusion: The oncological results of patients undergoing ISR are satisfactory, however, functional results should be taken into account when proposing this surgical procedure.

Highlights

  • Intersphinteric resection (ISR) allows preserve sphincter function in selected patients with rectal cancer (RC)

  • Inclusion criteria: Patients submitted to ISR by RC with curative intention

  • Analysis of functional evaluation were performed by JorgeWexner, LARS and Kirwan scale

Read more

Summary

Introduction

Intersphinteric resection (ISR) allows preserve sphincter function in selected patients with rectal cancer (RC). A mediados de los 90 Schiessel et al, proponen la resección anterior ultrabaja interesfintérica (RAUBIE); que además de obtener resultados oncológicos aceptables, permite preservar la mayor parte del complejo esfinteriano en pacientes seleccionados con un cáncer en los últimos 5 cm del recto siendo una alternativa a la RAP5,6. Si bien es cierto la RAUBIE permite preservar la mayor parte del complejo esfinteriano, puede producir alteraciones en la función evacuatoria que va a depender del nivel de la sección distal del esfínter anal interno (parcial, subtotal, extendida o total); lo que se acompañará de un grado variable de incontinencia fecal sumado al síndrome de resección anterior baja (síndrome LARS). El objetivo del presente estudio es analizar los resultados oncológicos y funcionales a largo plazo luego de una RAUBIE en pacientes con adenocarcinoma del recto inferior

Material y Métodos
RAUBIE Anastomótica Anastomótica
Findings
Responsabilidades éticas
Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.