Result of Multimodal Treatment Including Radiation Therapy for Squamous Cell Carcinomas of Maxillary Sinus: A Retrospective Study

Abstract

(26%) had adenoid cystic type maxillary sinus carcinoma. Nineteen patients (35%) were treated with IMRT, and 35 patients (65%) received 3DCRT. The median radiation doses for 3D-CRT and IMRTwere 62.1 and 63 Gy, respectively. Results: Over a median follow-up of 60 months (97 months for 3D-CRT and 34 months for IMRT), the 5-year locoregional recurrence-free survival (LRRFS), distant metastasis-free survival (DMFS), and overall survival (OS) rates were 66, 60.9, 50.1, and 67.2%, respectively. IMRT provided better 3-year LRRFS (89.2% versus 59.5%, pZ 0.035) and DMFS (94.7% versus 55.3%, p Z 0.042) rates than 3D-CRT. Out of total 13 local recurrences, the orbital wall (n Z 5) and infratemporal fossa (n Z 3) were the most common sites of local recurrence, and most local failures were marginal (n Z 8). Conclusions: Postoperative IMRT for patients with maxillary sinus carcinoma resulted in excellent disease control, and should be considered as the first treatment option in these cases. Author Disclosure: Y. Suh: None. L. Chang Geol: None. K. Keum: None.