Abstract
SINCE guanidinium ions have proved to be able to restore conduction of impulses by sodium-deficient frog A fibres1, it seemed desirable to ascertain whether other ionized compounds possessing a tetracovalent nitrogen atom (onium ions) also can substitute for sodium. An extensive, but not exhaustive, research has revealed that, in addition to guanidinium ions, five onium ions can restore conduction by sodium-deficient frog A fibres: formamidinium, amino-guanidinium, hydrazinium, hydroxylammonium and ammonium ions.
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