Restoration of Sinusoid Fenestrae Followed by Targeted Nanoassembly Delivery of an Anti‐Fibrotic Agent Improves Treatment Efficacy in Liver Fibrosis (Adv. Mater. 17/2023)

Abstract

Drug Delivery In article number 2212206, Ying Zhao, Xiaolong Qi, Guangjun Nie, and co-workers propose a liver sinusoid capillarization and hepatic stellate cells activation combined regulation strategy for liver fibrosis treatment. Liver sinusoid fenestrae restoration enhances the transport efficiency of nanomedicine through the liver sinusoid wall, which represents a promising approach for liver fibrosis treatment.