Abstract

BackgroundWith the growing awareness of restless legs syndrome (RLS), sensory disorders similar to RLS but initially confined to the arms, abdomen, and perineum have been reported. One of them is restless abdomen, which refers to a restless sensation in abdomen. Our study is designed to evaluate the clinical phenotype of restless abdomen and investigate its relationship with RLS.MethodsWe enrolled 10 patients with restless abdomen according to RLS diagnostic criteria, excluding the requiring of leg involvement. Laboratory examinations were performed to exclude mimics and notable comorbidities.ResultsAll 10 patients had RLS like symptoms in the abdomen and otherwise satisfied all other RLS diagnostic criteria, and responded to dopaminergic therapy.ConclusionsNeurologists and gastroenterologists should be aware that RLS-related restlessness can occur in extra-leg anatomy in the absence of episodes of worsening or augmentation of restlessness.

Highlights

  • With the growing awareness of restless legs syndrome (RLS), sensory disorders similar to RLS but initially confined to the arms, abdomen, and perineum have been reported

  • Restless legs syndrome (RLS) is a common neurologic sleep related movement disorder, characterized by unpleasant sensations localized deep in the lower limbs associated with an urge to move the legs, which worsens at rest, and in the evening or night hours [1,2,3]

  • The diagnosis of RLS was made according to the 2014 International Restless Legs Syndrome Study Group (IRLSSG) diagnostic criteria [2]

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Summary

Introduction

With the growing awareness of restless legs syndrome (RLS), sensory disorders similar to RLS but initially confined to the arms, abdomen, and perineum have been reported. As awareness of RLS has grown, several small reports describe sensory disorders similar to RLS initially confined to the arms, abdomen, and perineum [4,5,6,7,8,9,10]. These reported cases partially meet the diagnostic criteria of RLS. We collected 10 patients in whom RLS symptoms existed in the abdomen but satisfied all other RLS diagnostic criteria

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