Abstract
The difference of electrical potential measured across the isolated central portion of in vitro beef cornea was found to vary between 15 and 60 mv surface of the epithelium negative), with most frequent values between 30 and 35 mv. At the same time, transcorneal d.c.-resistance was found to be 5–7 kΩ cm 2 . The potential was easily lowered on decreasing corneal electrical resistance by clamping the tissue tightly into its lucite support. It was, however, reversibly increased when corneal resistance was lowered by substituting the sodium of the solution facing the epithelium with lithium, and decreased when the resistance was raised by replacing sodium with potassium.
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