Responses to corneal stimulation in vestibulospinal units of nucleus Deiters

Abstract

In precollicular decerebrated cats, the response patterns of antidromically identified vestibulospinal Deiters's neurons to stimulation of corneal receptors were investigated. These patterns were compared with the responses of the somatosensory receptors of the neck and limbs as well as with the vestibular input of the horizontal semicircular canals. Of the 162 antidromically driven Deiters's units, 23 were influenced, mainly bilaterally, from corneal receptors. Response latencies evoked by electrical stimulation of the cornea ranged from 6 to 16 ms (mean 12 ms). In 99 Deiters's cells, the influence from the limbs was examined: 51 revealed primarily an ipsilateral modulation from proximal joint receptors. Convergence with joint receptor input was found in 16 of the 18 corneally driven cells tested. Of the 115 cells tested, 15 neurons responded to neck rotation in the horizontal plane. A contribution from the lateral semicircular canals was found in 7 of the 101 examined Deiters's neurons. The connection of corneal receptors with the spinal motor system, via a vestibulospinal pathway, may mediate a nociceptive reflex protecting the eyes and the face.