Abstract
Abstract: Calcium silicate (CS) ceramics have good biocompatibility, high bonding strength with titanium alloy substrates, and are potential candidates for implant coating materials. The osteo-integration of coated implants with host bone tissue is greatly affected by the degradation of these coating materials in biological fluid. In this paper, zirconia adopted calcium silicate (CaO-ZrO2-SiO2, CZS) ceramic powder was synthesized. Plasma spraying was used to prepare the coating with Ti-6Al-4V as substrates. Human bone marrow-derived stromal cells (hBMSCs) culture system was used to evaluate the cytocompatibility of the CS and CZS coatings. Results showed that more cells were adhered to the CZS coating with high proliferation ratio than those on CS. The dissolution of CS and hereby elevated pH value were contributed to the decreased cell adhesion and proliferation.
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