Abstract
Response to White and Lewis: Letter to editor in response to Has Chlamydia trachomatis prevalence in young women in England, Scotland and Wales changed? Evidence from national probability surveys. Epidemiology and Infection. 2019.
Highlights
White and Lewis [1] comment on our article [2] highlighting the methodological issues arising when attempting to use the National survey of Attitudes and Sexual Lifestyles (NATSAL) to calibrate estimates of seroprevalence derived from data available by sources such as the Public Health England (PHE) Seroepidemiology Unit [3] and Health Survey for England [4]
It is not possible to use data on individuals who are tested for CT to make inferences about CT prevalence, or changes in CT prevalence over time, without information on how the CT prevalence relates to the probability of being tested, and how that changes over time [5,6,7]
Individuals may be tested for a number of reasons: following an ad hoc offer of opportunistic testing; as a result of symptoms; or concern about recent sexual encounters
Summary
White and Lewis [1] comment on our article [2] highlighting the methodological issues arising when attempting to use the National survey of Attitudes and Sexual Lifestyles (NATSAL) to calibrate estimates of seroprevalence derived from data available by sources such as the PHE Seroepidemiology Unit [3] and Health Survey for England [4].
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