Abstract

In our article, we show less increased coronary heart disease (CHD) risk in familial hypercholesterolemia (FH) patients with a low-density lipoprotein receptor ( LDLR ) mutation and with the APOE4/E4 genotype.1 We give several possible explanations, including decreased trapping at the surface of hepatocytes when fewer LDL receptors are available. These scenarios could have been accompanied by higher serum ApoE levels, compared with the earlier described lower ApoE levels in APOE4/E4 genotyped individuals.2 However, in …

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.