Abstract

We thank Dr Rosendorff1 for his interest in our editorial2 accompanying the article by Thune et al.3 The data presented by Thune et al3 indicated, in their words, an association (but no definite specification of cause and effect) between low blood pressure and adverse cardiovascular outcomes. As you suggest for their data, low pressure may not be an independent variable in the prediction of future adverse cardiovascular outcomes. Instead, low pressure may be the result of previous anterior myocardial infarction, Q-wave myocardial infarction, and/or degree of elevation of creatine kinase, genuine independent variables. We agree and would add …

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