Response to Testosterone and Blood Pressure: Is the Decreased Sodium Excretion the Missing Link?

Abstract

Thank you for your interest in our recent article, “Testosterone Supplementation in Male Obese Zucker Rats Reduces Body Weight and Improves Insulin Sensitivity But Increases Blood Pressure.”1 Thank you also for your suggestions and for sharing the information from your human studies showing the negative correlation between sodium excretion and total testosterone in your hypertensive cohort.2 Unfortunately, we did not measure sodium excretion in these studies.1 The rats were in sodium balance, so the …