Abstract

We thank Satoh and colleagues for their interest in our work published recently in Hypertension .1 In response to the Letter to the Editor by this group,2 we acknowledge that, as compared with aldosterone concentrations alone, the aldosterone/renin ratio (ARR) may be more reproducible and, hence, could be used as an index of inappropriate aldosterone activity. With respect to our recent work,1 further analysis did indeed show that plasma angiotensinogen (AGT) concentrations were related to ARR in participants with urinary Na+/K+ above the median ( r =0.21; P <0.0005) but not in those with urinary Na+/K+ below the median ( r =−0.03; P …

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