Abstract
Response to: "Questioning the evidence for BCI-based communication in the complete locked-in state".
Highlights
Dr Spuler claims that, in the paper by Chaudhary and colleagues [6], the change in the concentrations of oxy-hemoglobin (O2Hb) acquired from 20 different functional near-infrared spectroscopy channels were averaged, and further averaging was performed across trials and sessions
It has been argued that the sessions should be combined randomly to build a model; we argue that such a method might be valid for stable and invariant data but might be completely misleading for patients in completely locked-in state (CLIS)
The correlations of electroencephalogram (EEG) slow activity with performance, we reported in the original paper, underscore this point and demonstrate that such a relationship with lack of arousal and poor performance exists
Summary
Few groups have attempted to solve this problem, and only some have reported success in advancing the goal of providing a means of communication to patients in CLIS [4,5,6,7] In his commentary, Dr Spuler raises doubts about all the research efforts towards this goal but primarily about the results published in 2017 by Chaudhary and colleagues. We address the issues raised by Dr Spuler In his commentary, Dr Spuler claims that, in the paper by Chaudhary and colleagues [6], the change in the concentrations of oxy-hemoglobin (O2Hb) acquired from 20 different functional near-infrared spectroscopy (fNIRS) channels were averaged, and further averaging was performed across trials and sessions.
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