Abstract
It is common wisdom that chest pain that improves with nitroglycerin is probably ischemic in origin. However, the diagnostic and prognostic value of response to nitroglycerin in patients with chest pain has not been properly assessed. In a prospective study of 459 patients presenting to an emergency department with chest pain, researchers assessed whether a decrease in pain after the administration of a single nitroglycerin dose indicates an ischemic cause of the pain. The cause of chest pain was considered ischemic if the patient had active coronary artery disease (CAD), as defined by the presence of appropriate symptoms and any one of …
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