Abstract

We recently published the structure of a DNA double-helix induced by cytosine methylation and bromination, and called this conformation `E-DNA' to recognize the extended rise and eccentric trace of the helix backbone1. It has come to our attention from several readers, including H.-L. Ng and R.E. Dickerson, that the `E'-helix2 was previously used to describe a DNA fiber with approximately 152 screw symmetry and a rise of 3.25 A, which is not at all similar to the structure that we had published. It was not our intention to commandeer this name and, therefore, we will no longer use `E-DNA' to describe our structures. At the urging of the DNA structure community, and in particular because of Dickerson's arguments, we will not attempt to assign any new name, but will refer to our structure as the extended d(GGCGm5CC)2 conformation. We regret this oversight and any confusion that it may have caused.

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