Abstract
We thank Philips and O’Leary for their interesting comments on our study. They suggest that considering pubertal maturation as a potential confounding factor would have been important for the interpretation of the results, because it has been reported that in prepubertal boys, pulse-wave velocity is lower than in prepubertal girls, a difference that disappears after puberty.1 In our study, the very large majority of the participants was prepubertal, the mean age of the group conceived by assisted reproductive technologies (ART) tended to be lower, and there were proportionally more boys than girls in this group. Taken together, the combination of these factors would have been expected to result in lower pulse-wave velocity in the ART group than in the control group. This is exactly the opposite of what we found, which suggests that we may even have underestimated the detrimental effects …
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