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Abstract
We appreciate the opportunity of answering the points raised in the Letters to the Editor by Fragasso et al and Wiggers et al. Unfortunately, our results have been misinterpreted. The main purpose of our study was not to study the effect of acipimox on cardiac contractile function but to compare the responses in patients with heart failure with those in healthy volunteers.1 Therefore, a placebo group was not necessary. Our initial hypothesis was “that acute FFA depletion would result in …
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