Abstract
We thank Dr Yeo and coworkers for their interest in our study, in which we concluded that in patients presenting with acute headache and a normal head CT ≤6 hours after ictus, there is no added value of cerebrospinal fluid analysis.1 Dr Yeo and coworkers warn that our results need to be interpreted with caution. We cannot agree more, and that is why we emphasized (as Yeo et al do) that our results only can be extrapolated to high-volume tertiary care centers where head CT scans are interpreted by experienced neuroradiologists.1 However, Yeo et al end with the recommendation that in patients with acute headache but a negative early CT scan, a lumbar puncture should still be performed and perhaps even combined with a CT angiography. They illustrate their …
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