Abstract

We appreciate Dr Angelini's insights. The prevalence of anomalous coronary artery from the opposite sinus of Valsalva (ACAOS) that he reports from our article, however, was ACAOS with interarterial course (IAC). The actual prevalence of ACAOS was 0.14% (301 cases in 210 700 angiograms),1 a number consistent with several large, recently published series. For comparison, a Turkish group found a prevalence of 0.08% (11 cases in 12 457 angiograms),2 and recent series from India and China found prevalence to be 0.3% and 0.5%, respectively. We actually found that angiographers overreported rather than underreported this anomaly, and that only 57% of those patients initially coded as ACAOS in our registry were eventually confirmed. We agree that there are significant limitations …

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