Abstract
I agree with the objection raised by Dr Greenberg about my comment1 that implied that the continuous aortic flow augmentation system had a primary or direct effect on increasing cardiac output. Clearly, any increase in cardiac output would be secondary to a decrease in peripheral resistance associated with the distal aortic perfusion. The study design used in the Multicenter Trial of the Orqis Medical Cancion System for the Enhanced Treatment of Heart Failure Unresponsive to Medical Therapy (MOMENTUM) did in fact include a paired analysis, as noted by Dr Greenberg. The population of patients who develop worsening heart failure and become progressively unresponsive …
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