Abstract
Weingartner and colleagues have studied the association of serum phytosterol levels with cardiovascular outcomes using phytosterol levels as a biomarker of plant sterol intake. Unfortunately, circulating phytosterols are reflective of 2 very different and opposing processes. On the one hand, serum levels rise with increasing intake and can reflect a potentially beneficial effect of reduced cholesterol absorption efficiency.1 On the other hand, it is well established that serum phytosterol levels are also positively correlated …
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