Abstract
Response: We thank Dr Kazim Sheikh for his remarks on our article published in Stroke .1 Dr Sheikh raises an important question as to why it is necessary to combine several cardiovascular risk factors into a syndrome called the metabolic syndrome (MetS) and determine its association with stroke. The concept of the MetS is based on the fact that certain cardiovascular risk factors cluster in individuals.2,3 The presence of this clustering approximately doubles the risk of atherosclerotic vascular disease over 5 to 10 years.2 The 6 definitions of the Mets have been designed by expert panels to provide clinicians with a tool to identify individuals with an increased risk for diabetes and cardiovascular disease.4 Most previous studies on the MetS, however, …
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