Abstract
Response: We greatly appreciate the thoughtful comments by Drs Culp and Culp. First, we would like to acknowledge the excellent work the authors have done describing the angiographic cerebral vascular anatomy of the rabbit.1 The first draft of our paper was submitted in November 2006 with several revisions before final acceptance.2 On resubmission, we failed to cite the article by Culp et al, which had appeared in the interim. Concern is raised about the extent of MCA occlusion in our model and that infusion of thrombin may lead to a greater degree of vascular occlusion compared to that seen in the typical human stroke where there is only segmental occlusion …
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