Abstract
Response: We thank Dr Albin for his interest in our study. Dr Albin took issue with a statement in our article that whole-body (core) cooling must begin before cerebral cooling can begin. He correctly stated that there are ways around this, for example, “differential extracorporeal hypothermia perfusion.” We agree and we would like to clarify that in our article, we made the statement in the context of a discussion on the most widely used techniques/devices for inducing hypothermia, that is, external/surface cooling devices and endovascular devices, all of which cool the core first. Due to its ease of use and portability, the RhinoChill device may be used in the field maximizing hypothermia's potential neuroprotective effects, something that is not possible with extracorporeal perfusion. Dr Albin also commented on the lack of animal safety and efficacy data. We did mention 1 …
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