Abstract
We thank Thornton and Hess1 for their comments on 2 potential mechanisms that could account for the beneficial effects of exercise on cardiovascular structure and function. Exercise-induced effects on mitochondrial function and fluid loss/replacement have been proposed as intermediary processes. The protective effects of mitochondrial function against diabetes mellitus and cardiovascular aging are well documented. Thornton and Hess1 propose that exercise exerts a positive effect on mitochondrial function through …
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