Response to Dr Fried & Dr Kievit, and Dr Malhi et al.

Lianne Schmaal ,M-J Van Tol,Baptiste Couvy‐Duchesne ,Oliver Gruber ,Nic J Van Der Wee ,Brenda W J H Penninx ,Andrea Block ,Laura S Van Velzen ,M Czisch ,Beata R Godlewska ,Elisabeth Schramm ,Margaret J Wright ,Sarah E Medland ,Andrew M Mcintosh ,Bernd Krämer ,Katharina Wittfeld ,Carsten Konrad ,Dick J Veltman ,Jess E Sussmann ,Nathan A Gillespie ,Dieter Schoepf ,Heather C Whalley ,Claus Normann ,Elizabeth Loehrer ,Geoffrey B Hall ,Miguel E Rentería ,Greig I De Zubicaray ,Thomas Frodl ,Ilya M Veer ,Katie L Mcmahon ,Roberto Goya-Maldonado ,Bartosz Zurowski ,Theo G.m Van Erp ,Meike W Vernooij ,Neda Jahanshad ,Ian B Hickie ,Wiro J Niessen ,David Hoehn ,Hans‐Jörgen Grabe ,M Arfan Ikram ,Philipp G Sämann ,Katrin Hegenscheid ,Paul M Thompson ,Felix Fischer ,Henrik Walter ,Jim Lagopoulos ,Sean N Hatton ,Lachlan T Strike ,Derrek P Hibar

doi:10.1038/mp.2016.9

Abstract

Response to Dr Fried & Dr Kievit, and Dr Malhi et al.

Highlights

We thank Dr Fried & Dr Kievit, and Dr Malhi and colleagues for their insightful comments
That is why we reported meta-analytic results of subcortical volume differences in depressed patients stratified by stage of illness and age of onset.[3]
Brain structure was consistently altered across: (1) major depressive disorder (MDD) patients residing in the community or primary care, and (2) patients recruited from specialized mental health services, many of whom had more severe and recurrent MDD

Summary

Introduction

We thank Dr Fried & Dr Kievit, and Dr Malhi and colleagues for their insightful comments. We further clarify the design and outcome of our meta-analysis of subcortical volume differences between patients with major depressive disorder (MDD) and controls.

Results

Conclusion