Response to Deficiency of Bradykinin Receptor B2 Is not Detrimental in Experimental Stroke

Abstract

Our response was solicited by the editor based on the article by Kleinschnitz et al.1 We stand by our results that deficiency in the kinin B2 receptor exacerbates ischemic stroke deficits.2 Kleinschnitz et al1 doubt the possibility of dissecting 8 coronal sections from the mouse brain. In fact, it is easy to dissect each mouse brain into 8 serial sections using a 1-mm mouse brain matrix (RBM-2000C, ASI Instruments). We incorrectly identified the thickness as ≈2 mm instead of 1 mm per section (page 753), and cubic millimeters per rat instead of cubic millimeters per mouse (page 754).2 …