Response to: Comment on "The Impact of Chronic Tobacco Smoking on Retinal and Choroidal Thickness in Greek Population".

Abstract

We would like to thank Uzun for his observations [1]. Indeed choroidal thickness is influenced by several factors such as age, axial length, corneal curvature, intraocular pressure, systolic blood pressure, ocular perfusion pressure, and time of measurement [2]. Margolis and Spaide reported a 15.6-micron decrease in choroidal thickness every decade [3]; similarly, a 14-micron decrease every decade was reported by Ikuno et al. [4]. Wei et al. noted a thinning in subfoveal choroidal thickness among people around 65 years, estimating this reduction around 4 μm per year of age. Regarding axial length Wei et al. reported that the subfoveal thickness decreases by 15 microns for every increase in myopic refractive error of 1 D or by 32 microns for every increase in axial length of 1 mm [5]. Fujiwara et al. reported that choroidal thickness decreases by 12.7 μm for each decade of life and by 8.7 μm for each diopter of increasing myopia [6]. Gupta et al. supported that peripapillary choroidal thickness on average is decreased by 13.02 μm and 36.72 μm for each millimeter increase in axial length and corneal curvature, respectively. They also noted that each increment of myopic diopter resulted in the reduction of mean peripapillary choroidal thickness by 5.39 μm. On the other hand, they estimated that choroidal thickness augmented by 1.40 μm and 0.74 μm, when the intraocular pressure was increased by a millimeter of mercury or the retinal nerve fibre layer was raised by a micrometer, respectively [7].