Response to Comment on: Maruthur et al. Does Genetic Ancestry Explain Higher Values of Glycated Hemoglobin in African Americans? Diabetes 2011;60:2434–2438

Abstract

We appreciate the interest of Dagogo-Jack (1) in our study of genetic ancestry and HbA1c in African Americans (2). We interpret his major concerns as follows: 1 ) HbA1c values may have a glucose-independent genetic component and 2 ) in our study, adjustment for glucose did not fully account for HbA1c values ≥6.5%. Our goal was to evaluate if differences in genetic ancestry might explain differences in HbA1c between individuals of …