Abstract
We thank Drs. Doehner and Pfeiffer (1) for their letter in response to our article (2) on the association of metabolically healthy obese (MHO) phenotype with mortality. We used five definitions of metabolic health to show that for most definitions of metabolic health both metabolically healthy and unhealthy obese patients carry a similar, elevated risk of mortality. Doehner and Pfeiffer do not question the validity of our findings in relation to the MHO phenotype, but suggest that overweight and obesity may not be harmful at older ages and in those with a chronic disease. They suggest that “weight management should be …
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