Abstract
We thank Conway for her comment (1) on our article in Diabetes Care (2) on the risk of diabetes associated with elevated transferrin saturation levels in two follow-up studies (risk as hazard ratios and exposure preceding disease) and a case-control study (risk as odds ratio) with neither study being cross-sectional. We agree with Conway that the pathophysiology of diabetes is complex. We acknowledge that elevated cellular iron concentrations in insulin-sensitive tissue and the pancreatic …
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