Abstract
Re: Bernardi D, Tomassi O, Stefani M, Di Giacobbe A. Comment on “Clinical features and course of brain metastases in colorectal cancer: an experience from a single institution.” Curr Oncol 2013;20:e278. [...]
Highlights
Patients treated with surgery and whole-brain radiation therapy had improved survival compared with patients receiving other therapeutic modalities
Earlier detection of brain metastases may lead to better management and improved survival, there is not enough evidence to recommend routine brain imaging in long-surviving patients with metastatic colorectal cancer
Many questions are still unanswered concerning the role of systemic treatment after brain metastases diagnosis, the role of the molecular characteristics of these tumours, and the existence of predictive biomarkers[2,3]
Summary
Patients treated with surgery and whole-brain radiation therapy had improved survival compared with patients receiving other therapeutic modalities. There may be a selection bias, because these patients had a good performance status, solitary nodules, and well-controlled systemic disease.
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