Abstract
The pattern of individual responses to methylphenidate (10 mg) and factors that predict drug response in 46 children, 6-13 years old, with attention-deficit hyperactivity disorder (ADHD) were examined at the Department of Child and Adolescent Psychiatry, and the Rudolf Magnus Institute for Neurosciences, University of Utrecht, The Netherlands.
Highlights
Pediatric neurologists evaluating children with attention-deficit hyperactivity disorder (ADHD) are cognizant of the role of lead exposure in the etiology of learning and behavior problems
Treatment guidelines for lead exposure in children are outlined in an American Academy of Pediatrics Committee on Drugs report. (Berlin CM Jr et al Pediatrics July 1995;96:155-160)
RESPONSE PREDICTION TO METHYLPHENIDATE IN ADHD The pattern of individual responses to methylphenidate (10 mg) and factors that predict drug response in 46 children, 6-13 years old, with attention-deficit hyperactivity disorder (ADHD) were examined at the Department of Child and Adolescent Psychiatry, and the Rudolf Magnus Institute for Neurosciences, University of Utrecht, The Netherlands
Summary
The lead-safe home environment, careful supervision, and good personal hygiene of these children would explain the relatively low blood lead levels despite elevated environmental lead levels in the day care centers. Costly lead abatement efforts would have been unwarranted in this situation. Pediatric neurologists evaluating children with ADHD are cognizant of the role of lead exposure in the etiology of learning and behavior problems.
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