Abstract

INTRODUCTIONThe chronic respiratory disease strain #1 and #2 (CRD) used in this study was obtained from the Live Stock Service Laboratory in College Park and the branch laboratory of the Live Stock Sanitary Service Laboratory at Salisbury, Maryland. These strains were proven by reliable investigation to cause C.R.D. in fowl. They were used to initiate the following experiment. The virus was in the form of a 10 percent suspension of sinus exudate.MATERIALS AND METHODSThe following study was undertaken to determine whether these chronic respiratory disease strains of viruses could be transmitted to the suckling hamster. Suckling hamsters are much cheaper and easier to work with than chickens. Four lactating hamsters and their sucklings were placed in individual metal boxes with bedding. The sucklings were three days old. The sucklings from Group #1 and Group #2 were given strain #1 CRD by nasal instillation (0.03 ml. each nostril)… .

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