Abstract
SummaryThe response of plasma glucose and Nefa concentrations to DNP has been investigated. An overshoot in the transient response of plasma glucose concentration to a DNP-induced step increase in metabolic rate was apparent, with roughly 2 hours required for attainment of the steady state. We have failed, however, to detect any impairment of this response by prereserpinization. The Nefa concentration was found to increase continuously in response to DNP at a rate greater than that found in anesthetized control animals. The reserpinized animals differed only by an initial decrease in plasma Nefa concentration following DNP.
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