Abstract
Clinical, radiological and cytoenzymochemical studies of the results of using 243 metal-ceramic crowns during the year in 90 patients with healthy periodontium were carried out. The edges of the crowns were located in an equal number of teeth subgingivally and supragingivally. The activity of myeloperoxidase, alkaline phosphatase and cationic proteins in peripheral blood leukocytes was studied. It has been established that the subgingival location of the edge of the crowns causes the activation of the lysosomal apparatus of neutrophilic leukocytes and leads to the development of an inflammatory process in the marginal part of the gum. With the supragingival location of the edge of the crowns, there were no manifestations of the inflammatory process in the gingival margin. Changes in the biological activity of neutrophilic leukocytes precede the clinical manifestations of inflammation. Of the cytochemical parameters used in the study, the highest sensitivity was obtained when assessing the amount of cationic proteins in leukocytes.
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