Abstract

Access to upfront daratumumab for AL amyloidosis is expanding, but it is not universal. Bomsztyk etal. show that patients who do not receive front-line daratumumab can be effectively rescued with this agent, indicating that deep haematological response should be pursued tenaciously. Commentary on: Bomsztyk etal. Response rates to second-line treatment with daratumumab bortezomib dexamethasone (DVD) in relapsed/refractory light chain (AL) amyloidosis after initial bortezomib-based regime. Br J Haematol 2024 (Online ahead of print). doi: 10.1111/bjh.19529.

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