Abstract
To assess the burden of respiratory virus coinfections with severe acute respiratory coronavirus virus 2 (SARS-CoV-2), this study reviewed 4,818 specimens positive for SARS-CoV-2 and tested using respiratory virus multiplex testing. Coinfections with SARS-CoV-2 were uncommon (2.8%), with enterovirus or rhinovirus as the most prevalent target (88.1%). Respiratory virus coinfection with SARS-CoV-2 remains low 1 year into the coronavirus disease 2019 (COVID-19) pandemic.
Highlights
During the first 3 months of the pandemic in Alberta, Canada (March–May 2020), when all specimens submitted for SARSCoV-2 testing underwent respiratory viral multiplex testing, only 3.4% of those positive for SARS-CoV-2 were found to have a coinfecting respiratory virus.[4]
Respiratory viral coinfections occurred in 134 (2.8%; 95% confidence interval [CI], 2.4%–3.3%) of 4,818 COVID-19 cases, with significantly more in the pediatric group compared to adults: 10.0% versus 2.4%, respectively (P < .01) (Table 1)
respiratory syncytial virus (RSV), PIV, enterovirus or rhinovirus (ERV), and adenovirus were detected among both age categories
Summary
During the first 3 months of the pandemic in Alberta, Canada (March–May 2020), when all specimens submitted for SARSCoV-2 testing underwent respiratory viral multiplex testing, only 3.4% of those positive for SARS-CoV-2 were found to have a coinfecting respiratory virus.[4]. We assessed changes in frequency of respiratory virus coinfections with SARS-CoV-2 in adult and pediatric patients to determine whether routine on-demand multiplex respiratory virus testing in SARS-CoV-2 positive patients is beneficial later in the coronavirus disease 2019 (COVID-19) pandemic
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