Abstract
Understanding respiratory syncytial virus (RSV) circulation patterns is necessary to guide the timing of limited‐duration interventions such as vaccines. We describe RSV circulation over multiple seasons in three distinct counties of Kenya during 2006‐2018. Kilifi and Siaya counties each had consistent but distinct RSV seasonality, lasting on average 18‐22 weeks. Based on data from available years, RSV did not have a clear pattern of circulation in Nairobi. This information can help guide the timing of vaccines and immunoprophylaxis products that are under development.
Highlights
Respiratory syncytial virus (RSV) is a leading cause of severe acute respiratory infections in children < 5 years of age worldwide, with most of the disease burden occurring in developing countries.[1]
Several RSV vaccines and immunoprophylaxis products targeting young infants are in development, and may be available within the few years.[7]
In Nairobi, respiratory specimens were collected from all ages with influenza-like illness (ILI) or acute lower respiratory illness (ALRI) at an outpatient clinic, Tabitha Clinic, and with severe acute respiratory illness (SARI) at an inpatient hospital, Kenyatta National Hospital
Summary
Respiratory syncytial virus (RSV) is a leading cause of severe acute respiratory infections in children < 5 years of age worldwide, with most of the disease burden occurring in developing countries.[1]. Several RSV vaccines and immunoprophylaxis products targeting young infants are in development, and may be available within the few years.[7] the duration of protection of these products may be
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