Abstract
The magnitude of decrease in maximal oxygen uptake (VO2 max) in hypoxia (H) is more pronounced in male endurance athletes. In these subjects, high pulmonary ventilation (VE) could be beneficial in maintaining VO2 max in H [1]. Because females have smaller chest walls and narrower airways than males, VE during intensive exercise is mechanically limited [2]. Thus, it is hypothesised that in females, respiratory response and mechanics influenced the magnitude of decrease in VO2 max in H relative to males, despite lower VO2 max in females than in males. To test this hypothesis, we studied 22 healthy males and females as they performed an exhaustive cycling test in H and normoxia (N) conditions.
Highlights
The magnitude of decrease in maximal oxygen uptake (VO2 max) in hypoxia (H) is more pronounced in male endurance athletes
The % dVO2 max in H was significantly correlated to the extent of change in VE max (r = 0.79, p < 0.05)
In comparison with N, work of breathing (WOB)/VE in H tended to be lower in males (−13.1%) whereas it was 14.6% higher in females
Summary
The magnitude of decrease in maximal oxygen uptake (VO2 max) in hypoxia (H) is more pronounced in male endurance athletes In these subjects, high pulmonary ventilation (VE) could be beneficial in maintaining VO2 max in H [1]. It is hypothesised that in females, respiratory response and mechanics influenced the magnitude of decrease in VO2 max in H relative to males, despite lower VO2 max in females than in males. To test this hypothesis, we studied 22 healthy males and females as they performed an exhaustive cycling test in H and normoxia (N) conditions
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