Abstract

Introduction: Glutaraldehyde is still used for sterilization of endoscopes in Egypt and known to be associated with many respiratory problems, so this study aims to establish control program guidelines to promote the respiratory health of endoscopy nurses in Zagazig University Hospitals with the objectives to assess the frequency of respiratory health problems among endoscopy nurses and to identify associated occupational and personal risk factors. Methods: A comparative cross-sectional study carried on 42 endoscopy nurses exposed to glutaraldehyde compared to non-exposed 84 nurses working at outpatient clinics. All nurses were subjected to a questionnaire (socio-demographic and occupational characteristics, chronic respiratory problems), checklist for assessment of glutaraldehyde related work practice and pulmonary function tests. Results: Chronic cough was found in 52.0% of endoscopy nurses while asthma was only in 19.0% of nurse. Chronic respiratory problems increased in endoscopy nurses with increased work duration, poor work practices especially handling procedures and lack of training. All ventilatory lung function parameters of endoscopy nurses showed statistically significant decline with both increased work duration ≥ 15 years and increased working hours ≥ 36 hours per week. Majority of endoscopy nurses 30.0% had mild airflow obstruction. Conclusions: Highlighting the respiratory health problems and airway obstruction resulting from exposure to glutaraldehyde will raise the importance to use safer alternatives. Results will lead to implementing of training programs for proper cleaning and sterilization processes, also raising awareness and providing information about proper work practices of handling hazardous substances.

Highlights

  • Glutaraldehyde is still used for sterilization of endoscopes in Egypt and known to be associated with many respiratory problems, so this study aims to establish control program guidelines to promote the respiratory health of endoscopy nurses in Zagazig University Hospitals with the objectives to assess the frequency of respiratory health problems among endoscopy nurses and to identify associated occupational and personal risk factors

  • Forty-two nurses from endoscopy units exposed to glutaraldehyde and 84 nurses from outpatient clinics in University hospitals engaged as control group participated in this study

  • Assessment of endoscopy nurses practice, results showed that 67.5% of them had poor transportation & storage, while 66.7% had poor usage & handling procedures of GA

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Summary

Introduction

Glutaraldehyde is still used for sterilization of endoscopes in Egypt and known to be associated with many respiratory problems, so this study aims to establish control program guidelines to promote the respiratory health of endoscopy nurses in Zagazig University Hospitals with the objectives to assess the frequency of respiratory health problems among endoscopy nurses and to identify associated occupational and personal risk factors. Chronic respiratory problems increased in endoscopy nurses with increased work duration, poor work practices especially handling procedures and lack of training. Conclusions: Highlighting the respiratory health problems and airway obstruction resulting from exposure to glutaraldehyde will raise the importance to use safer alternatives. Nurses and other health care workers are in danger of exposure while cleaning equipment and work surfaces. Both of these chemicals are widely used for its effectiveness, they are associated with serious human health problems [1]. Glutaraldehyde is an aliphatic dialdehyde colorless liquid with a pungent odor It is used in a wide range in medical field mainly for disinfection of medical instruments including endoscopes [2]. For the past 40 years, GA (in 2–4% solution with water) has been the primary chemical used for HLD [3]

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