Respiratory Failure Associated with Ascariasis in a Patient with Immunodeficiency.

Lanocha Aleksandra,Kosik-Bogacka Danuta,Lanocha-Arendarczyk Natalia,Zdziarska Barbara,Guzicka-Kazimierczak Renata,Marzec-Lewenstein Ewa

doi:10.1155/2016/4070561

Lanocha Aleksandra, Kosik-Bogacka Danuta + Show 4 more

Open Access

https://doi.org/10.1155/2016/4070561

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Abstract

In industrialized countries, risk groups for parasitic diseases include travelers, recent immigrants, and patients with immunodeficiency following chemotherapy and radiotherapy and AIDS. A 66-year-old Polish male was admitted in December 2012 to the Department of Haematology in a fairly good general condition. On the basis of cytological, cytochemical, immunophenotypic, and cytogenetic analysis of bone marrow, the patient was diagnosed with acute myeloblastic leukemia. On the 7th day of hospitalization in the Department of Haematology, patient was moved to the Intensive Care Unit (ICU) due to acute respiratory and circulatory failure. In March 2013, 3 months after the onset of respiratory failures, a mature form of Ascaris spp. appeared in the patient's mouth. This report highlights the importance of considering an Ascaris infection in patients with low immunity presenting no eosinophilia but pulmonary failure in the central countries of Europe.

Highlights

Ascaris lumbricoides (Linnaeus, 1758) is the most common soil-transmitted intestinal nematode affecting humans and causing significant medical problems, especially in developing countries
We present an unusual ascariasis and respiratory failure in a patient with acute myeloblastic leukemia (AML)
On the basis of cytological, cytochemical, immunophenotypic, and cytogenetic analysis of bone marrow in December 2012, the patient was diagnosed with acute myeloblastic leukemia

Summary

Introduction

Ascaris lumbricoides (Linnaeus, 1758) is the most common soil-transmitted intestinal nematode affecting humans and causing significant medical problems, especially in developing countries. The pig roundworm Ascaris suum (Goeze 1758) has been reported to be able to infect humans and develop into the adult stage. Both the morphology and development cycles of A. lumbricoides and A. suum are very similar and the identification of these species in the environment is very difficult [6]. Clinical manifestations are different at each stage of the infection This helminth usually lives in the small intestine but can cause intestinal obstruction or perforation peritonitis, common in childhood [7]. We present an unusual ascariasis and respiratory failure in a patient with acute myeloblastic leukemia (AML)

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