Respiratory drive during sudden cold water immersion

Abstract

Sudden decreases in cutaneous temperature induce an immediate ventilatory response, which has been termed the inspiratory or ‘gasp’ reflex. This respiratory response has been implicated as a contributing factor to cold water immersion drowning. In the present study, five subjects wearing either shorts or a variety of thermal protective apparel were immersed on separate occasions in 10 °C water. The observed peak mean skin temperature cooling rates (dT̄s/dt) for the different conditions varied from 6.9 ± 2.1 °C/min for the shorts condition to 1.8 ± 0.3 °C/min for a helicopter pilot suit made of cotton ventile material. During the immersion, recordings were made of respiratory drive, as indicated by the mouth occlusion pressure at 100 msec following the onset of inspiration (P 0.1). The respiratory drive, an indicator of central inspiratory activity, correlated well with peak dT̄s/dt. The slope P 0.1/(dT̄s/dt) was subject dependent and did not appear to be related to body composition. The substantial intersubject variability in the respiratory response is suggested to result from differences in the central integration of thermoafferent information. It is concluded that the inspiratory reflex is the result of cutaneous thermoreceptor activity.