Abstract
Chronic obstructive pulmonary disease (COPD) is predicted to be the third leading cause of death in the United States by 2020. Approximately 125,000 people die yearly from acute exacerbations of the disease. Once intubation and mechanical ventilation become necessary, the death rate increases. To avoid the need for ventilator use we have developed a new device (the Hemolung), which is an integrated pump/oxygenator that functions at low blood flow rates (250–500 ml/min) equivalent to those used in renal dialysis. The small priming volume (190 ml), reduced membrane surface area (0.5 m2), and use of a percutaneously inserted dual lumen venous catheter (15 Fr) to provide blood inflow and outflow make the entire system suitable for repetitive use in patients with hypercapnic acute respiratory failure. We report here 7-day animal data stressing the hemocompatibility and gas exchange capabilities of the device.
Highlights
The aim of this study was to elucidate the impact of ICU-acquired infection on ICU and hospital mortality
The goal from this study is to evaluate weaning predictor indexes in patients during weaning from mechanical ventilation (MV)
This study aims to evaluate the effects of the threshold in such situations
Summary
The aim of this study was to elucidate the impact of ICU-acquired infection on ICU and hospital mortality. Methods A total of 48 community patients (36 men, 11 women, age 50.17 ± 17.974 years, APACHE II score 13.51 ± 6.153) who were expected to stay in the ICU for >5 days were included in this study. Specific examples of feedback are as follows: ‘good update of management plan reinforces need for taking into account concurrent medication when resuscitating patients’, ‘nice simple messages with good starting points for trying to deal with these complicated patients’, ‘useful data on risk of recurrence as this is a question often asked by patients’ This feedback was encouraging as it showed how the primary care professionals planned to change their practice to improve patient outcomes as a result of the learning. The course was considered excellent by 63% of the participants and good by 36%
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