Abstract
Radiation therapy of pancreatic cancer is challenging due to the close proximity of the target and surrounding organs at risk (OARs). Both target and OARs exhibit respiratory-correlated motion. Efforts have been devoted to address the target motion, but the dosimetric effect of OAR motion is largely unknown. In the current study, we investigated the motion of duodenum, the most dose-limiting OAR, and its dosimetric implications in hypofractionated stereotactic body radiation therapy (HFSBRT) of pancreatic head tumors.
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