Abstract
Up to half of the adult population has allergen specific immunoglobin E antibodies (sIgE)1,2 . Even though females and males are not equally affected relatively little is known regarding mechanisms behind differences in IgE sensitization between females and males. IgE poly-sensitization has been defined as IgE reactivity to several nonrelated (or not obviously related) allergenic source materials and has been shown to increase with age and correlate with disease expression and multimorbidity3,4 . Although females and males do not seem to differ regarding IgE poly-sensitization in adulthood,5 a recent study indicate that IgE poly-sensitization is more common among boys than girls in childhood5 .
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