Abstract
The resolution of racemic α-hydroxy-H-phosphinic acid with enantiopure 1-phenylethylamines via diastereomeric salt formation was investigated. X-Ray crystallographic analysis of the salt revealed that ( R)-1-phenylethylamine to be efficient resolving agent for obtaining a single enantiomer of [α-hydroxy-( o-chlorophenyl)methyl]phosphinic acid. Resolving racemic α-hydroxy-H-phosphinic acid with ( S)-2-phenylethylamine also gave access to ( S)-α-hydroxyalkylphosphinic acid in good yield.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
