Abstract
This chapter contains sections titled: Introduction Physical Enantioseparation – Preferential Crystallization Chemical Enantioseparation – Diastereomeric Salt Formation The Bridge Between Preferential Crystallization and Diastereomeric Salt Formation Process Research on the Enantioseparation of Racemates by Diastereomeric Salt Formation The Role of Water in the Stabilization of Less-soluble Diastereomeric Salts – A Key Intermediate for the Synthesis of Duloxetine,3-(Methylamino)-1-(2-thienyl)propan-1-ol Reciprocal Enantioseparation – A Key Intermediate for ACE Inhibitors, 2-Hydroxy-4-phenylbutyric Acid, and 1-(4-Methylphenyl)ethylamine Solvent Switch – A Key Intermediate for Lysine Production, α-Amino-ε-caprolactam Examples of Enantioseparations in the Pharmaceutical Industry References
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